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Hop/Sti1 phosphorylation inhibits its co-chaperone function
In eukaryotes, the molecular chaperones Hsp90 and Hsp70 are connected via the co-chaperone Sti1/Hop, which allows transfer of clients. Here, we show that the basic functions of yeast Sti1 and human Hop are conserved. These include the simultaneous binding of Hsp90 and Hsp70, the inhibition of the AT...
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| Udgivet i: | EMBO Rep |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BlackWell Publishing Ltd
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4328751/ https://ncbi.nlm.nih.gov/pubmed/25504578 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201439198 |
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