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Dynamics of the regulation of Hsp90 by the co-chaperone Sti1
In eukaryotic cells, Hsp90 chaperones assist late folding steps of many regulatory protein clients by a complex ATPase cycle. Binding of clients to Hsp90 requires prior interaction with Hsp70 and a transfer reaction that is mediated by the co-chaperone Sti1/Hop. Sti1 furthers client transfer by inhi...
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| Hoofdauteurs: | , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Publishing Group
2012
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3321184/ https://ncbi.nlm.nih.gov/pubmed/22354036 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.37 |
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