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Differences in conformational dynamics within the Hsp90 chaperone family reveal mechanistic insights

The molecular chaperones of the Hsp90 family are essential in all eukaryotic cells. They assist late folding steps and maturation of many different proteins, called clients, that are not related in sequence or structure. Hsp90 interaction with its clients appears to be coupled to a series of conform...

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Detalhes bibliográficos
Publicado no:Front Mol Biosci
Main Authors: Graf, Christian, Lee, Chung-Tien, Eva Meier-Andrejszki, L., Nguyen, Minh T. N., Mayer, Matthias P.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4428384/
https://ncbi.nlm.nih.gov/pubmed/25988145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2014.00004
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