Hsp90 regulates the dynamics of its cochaperone Sti1 and the transfer of Hsp70 between modules

The cochaperone Sti1/Hop physically links Hsp70 and Hsp90. The protein exhibits one binding site for Hsp90 (TPR2A) and two binding sites for Hsp70 (TPR1 and TPR2B). How these sites are used remained enigmatic. Here we show that Sti1 is a dynamic, elongated protein that consists of a flexible N-termi...

全面介紹

Na minha lista:
書目詳細資料
發表在:Nat Commun
Main Authors: Röhl, Alina, Wengler, Daniela, Madl, Tobias, Lagleder, Stephan, Tippel, Franziska, Herrmann, Monika, Hendrix, Jelle, Richter, Klaus, Hack, Gordon, Schmid, Andreas B., Kessler, Horst, Lamb, Don C., Buchner, Johannes
格式: Artigo
語言:Inglês
出版: Nature Pub. Group 2015
主題:
Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403447/
https://ncbi.nlm.nih.gov/pubmed/25851214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7655
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍