Hsp90 regulates the dynamics of its cochaperone Sti1 and the transfer of Hsp70 between modules

The cochaperone Sti1/Hop physically links Hsp70 and Hsp90. The protein exhibits one binding site for Hsp90 (TPR2A) and two binding sites for Hsp70 (TPR1 and TPR2B). How these sites are used remained enigmatic. Here we show that Sti1 is a dynamic, elongated protein that consists of a flexible N-termi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nat Commun
Egile Nagusiak: Röhl, Alina, Wengler, Daniela, Madl, Tobias, Lagleder, Stephan, Tippel, Franziska, Herrmann, Monika, Hendrix, Jelle, Richter, Klaus, Hack, Gordon, Schmid, Andreas B., Kessler, Horst, Lamb, Don C., Buchner, Johannes
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Pub. Group 2015
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403447/
https://ncbi.nlm.nih.gov/pubmed/25851214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7655
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak