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Hop/Sti1 phosphorylation inhibits its co-chaperone function

In eukaryotes, the molecular chaperones Hsp90 and Hsp70 are connected via the co-chaperone Sti1/Hop, which allows transfer of clients. Here, we show that the basic functions of yeast Sti1 and human Hop are conserved. These include the simultaneous binding of Hsp90 and Hsp70, the inhibition of the AT...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:EMBO Rep
Päätekijät: Röhl, Alina, Tippel, Franziska, Bender, Evelyn, Schmid, Andreas B, Richter, Klaus, Madl, Tobias, Buchner, Johannes
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BlackWell Publishing Ltd 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4328751/
https://ncbi.nlm.nih.gov/pubmed/25504578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201439198
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