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Wobble Pairs of the HDV Ribozyme Play Specific Roles in Stabilization of Active Site Dynamics
The hepatitis delta virus (HDV) is the only known human pathogen whose genome contains a catalytic RNA motif (ribozyme). The overall architecture of the HDV ribozyme is that of a double-nested pseudoknot, with two GU pairs flanking the active site. Although extensive studies have shown that mutation...
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| izdano v: | Phys Chem Chem Phys |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2015
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4324322/ https://ncbi.nlm.nih.gov/pubmed/25631765 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4cp05083e |
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