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Targeting histone lysine demethylases — Progress, challenges, and the future()
N-Methylation of lysine and arginine residues has emerged as a major mechanism of transcriptional regulation in eukaryotes. In humans, N(ε)-methyllysine residue demethylation is catalysed by two distinct subfamilies of demethylases (KDMs), the flavin-dependent KDM1 subfamily and the 2-oxoglutarate-...
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| Publicat a: | Biochim Biophys Acta Gene Regul Mech |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Elsevier
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4316176/ https://ncbi.nlm.nih.gov/pubmed/24859458 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagrm.2014.05.009 |
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