HSP90 Supports Tumor Growth and Angiogenesis through PRKD2 Protein Stabilization

The kinase PRKD2 (protein kinase D) is a crucial regulator of tumor cell-endothelial cell communication in gastrointestinal tumors and glioblastomas, but its mechanistic contributions to malignant development are not understood. Here, we report that the oncogenic chaperone HSP90 binds to and stabili...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cancer Res
Egile Nagusiak: Azoitei, Ninel, Diepold, Kristina, Brunner, Cornelia, Rouhi, Arefeh, Genze, Felicitas, Becher, Alexander, Kestler, Hans, van Lint, Johan, Chiosis, Gabriela, Koren, John, Fröhling, Stefan, Scholl, Claudia, Seufferlein, Thomas
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4315623/
https://ncbi.nlm.nih.gov/pubmed/25297628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-1017
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak