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Physical plasma-triggered ROS induces tumor cell death upon cleavage of HSP90 chaperone
HSP90 is a ubiquitously expressed molecular chaperone implicated in the correct folding and maturation of a plethora of proteins including protein kinases and transcription factors. While disruption of chaperone activity was associated with augmented cancer cell death and decreased tumor growth both...
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| Publicado no: | Sci Rep |
|---|---|
| Principais autores: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6412052/ https://ncbi.nlm.nih.gov/pubmed/30858416 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-38580-0 |
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