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Sildenafil triggers tumor lethality through altered expression of HSP90 and degradation of PKD2
The repurposing of existing drugs has emerged as an attractive additional strategy to the development of novel compounds in the fight against cancerous diseases. Inhibition of phosphodiesterase 5 (PDE5) has been claimed as a potential approach to target various cancer subtypes in recent years. Howev...
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| Publicado no: | Carcinogenesis |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7566345/ https://ncbi.nlm.nih.gov/pubmed/31917403 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgaa001 |
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