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Sildenafil triggers tumor lethality through altered expression of HSP90 and degradation of PKD2

The repurposing of existing drugs has emerged as an attractive additional strategy to the development of novel compounds in the fight against cancerous diseases. Inhibition of phosphodiesterase 5 (PDE5) has been claimed as a potential approach to target various cancer subtypes in recent years. Howev...

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Bibliografiske detaljer
Udgivet i:Carcinogenesis
Main Authors: Chen, Lu, Liu, Yang, Becher, Alexander, Diepold, Kristina, Schmid, Evi, Fehn, Adrian, Brunner, Cornelia, Rouhi, Arefeh, Chiosis, Gabriela, Cronauer, Marcus, Seufferlein, Thomas, Azoitei, Ninel
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7566345/
https://ncbi.nlm.nih.gov/pubmed/31917403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgaa001
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