Sildenafil triggers tumor lethality through altered expression of HSP90 and degradation of PKD2

The repurposing of existing drugs has emerged as an attractive additional strategy to the development of novel compounds in the fight against cancerous diseases. Inhibition of phosphodiesterase 5 (PDE5) has been claimed as a potential approach to target various cancer subtypes in recent years. Howev...

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Detalhes bibliográficos
Publicado no:Carcinogenesis
Main Authors: Chen, Lu, Liu, Yang, Becher, Alexander, Diepold, Kristina, Schmid, Evi, Fehn, Adrian, Brunner, Cornelia, Rouhi, Arefeh, Chiosis, Gabriela, Cronauer, Marcus, Seufferlein, Thomas, Azoitei, Ninel
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Carcinogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7566345/
https://ncbi.nlm.nih.gov/pubmed/31917403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgaa001
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