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Computational Study of Correlated Domain Motions in the AcrB Efflux Transporter

As active part of the major efflux system in E. coli bacteria, AcrB is responsible for the uptake and pumping of toxic substrates from the periplasm toward the extracellular space. In combination with the channel protein TolC and membrane fusion protein AcrA, this efflux pump is able to help the bac...

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Détails bibliographiques
Publié dans:Biomed Res Int
Auteurs principaux: Schulz, Robert, Vargiu, Attilio V., Ruggerone, Paolo, Kleinekathöfer, Ulrich
Format: Artigo
Langue:Inglês
Publié: Hindawi Publishing Corporation 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4313061/
https://ncbi.nlm.nih.gov/pubmed/25685792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/487298
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