Localization of APOL1 Protein and mRNA in the Human Kidney: Nondiseased Tissue, Primary Cells, and Immortalized Cell Lines

Although APOL1 gene variants are associated with nephropathy in African Americans, little is known about APOL1 protein synthesis, uptake, and localization in kidney cells. To address these questions, we examined APOL1 protein and mRNA localization in human kidney and human kidney-derived cell lines....

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Détails bibliographiques
Publié dans:J Am Soc Nephrol
Auteurs principaux: Ma, Lijun, Shelness, Gregory S., Snipes, James A., Murea, Mariana, Antinozzi, Peter A., Cheng, Dongmei, Saleem, Moin A., Satchell, Simon C., Banas, Bernhard, Mathieson, Peter W., Kretzler, Matthias, Hemal, Ashok K., Rudel, Lawrence L., Petrovic, Snezana, Weckerle, Allison, Pollak, Martin R., Ross, Michael D., Parks, John S., Freedman, Barry I.
Format: Artigo
Langue:Inglês
Publié: American Society of Nephrology 2015
Sujets:
Basic Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4310650/
https://ncbi.nlm.nih.gov/pubmed/25012173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2013091017
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