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Localization of APOL1 Protein and mRNA in the Human Kidney: Nondiseased Tissue, Primary Cells, and Immortalized Cell Lines

Although APOL1 gene variants are associated with nephropathy in African Americans, little is known about APOL1 protein synthesis, uptake, and localization in kidney cells. To address these questions, we examined APOL1 protein and mRNA localization in human kidney and human kidney-derived cell lines....

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Ma, Lijun, Shelness, Gregory S., Snipes, James A., Murea, Mariana, Antinozzi, Peter A., Cheng, Dongmei, Saleem, Moin A., Satchell, Simon C., Banas, Bernhard, Mathieson, Peter W., Kretzler, Matthias, Hemal, Ashok K., Rudel, Lawrence L., Petrovic, Snezana, Weckerle, Allison, Pollak, Martin R., Ross, Michael D., Parks, John S., Freedman, Barry I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4310650/
https://ncbi.nlm.nih.gov/pubmed/25012173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2013091017
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