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An acidic environment induces APOL1-associated mitochondrial fragmentation
BACKGROUND: Apolipoprotein L1 gene (APOL1) G1 and G2 kidney-risk variants (KRVs) cause chronic kidney disease in African Americans, inducing mitochondrial dysfunction. Modifying factors are required, because a minority of individuals with APOL1 high-risk genotypes develop nephropathy. Given that APO...
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| Publicado no: | Am J Nephrol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7511450/ https://ncbi.nlm.nih.gov/pubmed/32866949 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000509989 |
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