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Suppression of adrenal βarrestin1-dependent aldosterone production by ARBs: head-to-head comparison
The known angiotensin II (AngII) physiological effect of aldosterone synthesis and secretion is mediated by either G(q/11) proteins or βarrestin1 (βarr1), both of which can couple to its type 1 receptors (AT(1)Rs), present in adrenocortical zona glomerulosa (AZG) cell membranes. In the present study...
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| Publicado en: | Sci Rep |
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| Autores principales: | , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Publishing Group
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4309955/ https://ncbi.nlm.nih.gov/pubmed/25631300 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep08116 |
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