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The Resveratrol Trimer Miyabenol C Inhibits β-Secretase Activity and β-Amyloid Generation
Accumulation and deposition of amyloid-β peptide (Aβ) in the brain is a primary cause of the pathogenesis of Alzheimer’s disease (AD). Aβ is generated from amyloid-β precursor protein (APP) through sequential cleavages first by β-secretase and then by γ-secretase. Inhibiting β-secretase activity is...
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| Publicado no: | PLoS One |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4309453/ https://ncbi.nlm.nih.gov/pubmed/25629409 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115973 |
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