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The demonstration of αKlotho deficiency in human chronic kidney disease with a novel synthetic antibody
BACKGROUND: αKlotho is the prototypic member of the Klotho family and is most highly expressed in the kidney. αKlotho has pleiotropic biologic effects, and in the kidney, its actions include regulation of ion transport, cytoprotection, anti-oxidation and anti-fibrosis. In rodent models of chronic ki...
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| Publicado en: | Nephrol Dial Transplant |
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| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4309192/ https://ncbi.nlm.nih.gov/pubmed/25324355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ndt/gfu291 |
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