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Klotho and kidney disease

Klotho is a single-pass transmembrane protein that exerts its biological functions through multiple modes. Membrane-bound Klotho acts as coreceptor for the major phosphatonin fibroblast growth factor-23 (FGF23), while soluble Klotho functions as an endocrine substance. In addition to in the distal n...

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Bibliografiske detaljer
Main Authors: Hu, Ming-Chang, Kuro-o, Makoto, Moe, Orson W.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3227531/
https://ncbi.nlm.nih.gov/pubmed/21170871
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