Klotho Deficiency Causes Vascular Calcification in Chronic Kidney Disease

Soft-tissue calcification is a prominent feature in both chronic kidney disease (CKD) and experimental Klotho deficiency, but whether Klotho deficiency is responsible for the calcification in CKD is unknown. Here, wild-type mice with CKD had very low renal, plasma, and urinary levels of Klotho. In h...

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Detalhes bibliográficos
Main Authors: Hu, Ming Chang, Shi, Mingjun, Zhang, Jianning, Quiñones, Henry, Griffith, Carolyn, Kuro-o, Makoto, Moe, Orson W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2011
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014041/
https://ncbi.nlm.nih.gov/pubmed/21115613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2009121311
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