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Klotho and Chronic Kidney Disease

Through alternative splicing, Klotho protein exists both as a secreted and a membrane form whose extracellular domain could be shed from the cell surface by secretases and released into the circulation to act as endocrine factor. Unlike membrane Klotho which functions as a coreceptor for fibroblast...

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Detalles Bibliográficos
Main Authors: Hu, Ming Chang, Kuro-o, Makoto, Moe, Orson W.
Formato: Artigo
Idioma:Inglês
Publicado: 2013
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911771/
https://ncbi.nlm.nih.gov/pubmed/23652549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000346778
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