Renal Production, Uptake, and Handling of Circulating αKlotho

αKlotho is a multifunctional protein highly expressed in the kidney. Soluble αKlotho is released through cleavage of the extracellular domain from membrane αKlotho by secretases to function as an endocrine/paracrine substance. The role of the kidney in circulating αKlotho production and handling is...

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Vydáno v:J Am Soc Nephrol
Hlavní autoři: Hu, Ming Chang, Shi, Mingjun, Zhang, Jianning, Addo, Tayo, Cho, Han Ju, Barker, Sarah L., Ravikumar, Priya, Gillings, Nancy, Bian, Ao, Sidhu, Sachdev S., Kuro-o, Makoto, Moe, Orson W.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Nephrology 2016
Témata:
Basic Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4696570/
https://ncbi.nlm.nih.gov/pubmed/25977312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2014101030
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