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αKlotho Mitigates Progression of AKI to CKD through Activation of Autophagy

AKI confers increased risk of progression to CKD. αKlotho is a cytoprotective protein, the expression of which is reduced in AKI, but the relationship of αKlotho expression level to AKI progression to CKD has not been studied. We altered systemic αKlotho levels by genetic manipulation, phosphate loa...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:J Am Soc Nephrol
Päätekijät: Shi, Mingjun, Flores, Brianna, Gillings, Nancy, Bian, Ao, Cho, Han Jun, Yan, Shirley, Liu, Yang, Levine, Beth, Moe, Orson W., Hu, Ming Chang
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society of Nephrology 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4978045/
https://ncbi.nlm.nih.gov/pubmed/26701976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015060613
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