αKlotho Mitigates Progression of AKI to CKD through Activation of Autophagy

AKI confers increased risk of progression to CKD. αKlotho is a cytoprotective protein, the expression of which is reduced in AKI, but the relationship of αKlotho expression level to AKI progression to CKD has not been studied. We altered systemic αKlotho levels by genetic manipulation, phosphate loa...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Am Soc Nephrol
Egile Nagusiak: Shi, Mingjun, Flores, Brianna, Gillings, Nancy, Bian, Ao, Cho, Han Jun, Yan, Shirley, Liu, Yang, Levine, Beth, Moe, Orson W., Hu, Ming Chang
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Nephrology 2016
Gaiak:
Basic Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4978045/
https://ncbi.nlm.nih.gov/pubmed/26701976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015060613
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