Downregulation of autophagy is associated with severe ischemia-reperfusion-induced acute kidney injury in overexpressing C-reactive protein mice

C-reactive protein (CRP), was recently reported to be closely associated with poor renal function in patients with acute kidney injury (AKI), but whether CRP is pathogenic or a mere biomarker in AKI remains largely unclear. Impaired autophagy is known to exacerbate renal ischemia-reperfusion injury...

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Bibliographic Details
Published in:PLoS One
Main Authors: Bian, Ao, Shi, Mingjun, Flores, Brianna, Gillings, Nancy, Li, Peng, Yan, Shirley Xiao, Levine, Beth, Xing, Changying, Hu, Ming Chang
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5590740/
https://ncbi.nlm.nih.gov/pubmed/28886014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0181848
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