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Intracerebral injection of preformed synthetic tau fibrils initiates widespread tauopathy and neuronal loss in the brains of tau transgenic mice
Neurofibrillary tangles composed of hyperphosphorylated fibrillized tau are found in numerous tauopathies including Alzheimer's disease. Increasing evidence suggests that tau pathology can be transmitted from cell-to-cell; however the mechanisms involved in the initiation of tau fibrillization...
Zapisane w:
| Wydane w: | Neurobiol Dis |
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| Główni autorzy: | , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2014
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4303592/ https://ncbi.nlm.nih.gov/pubmed/25220759 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2014.08.032 |
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