טוען...

Intracerebral injection of preformed synthetic tau fibrils initiates widespread tauopathy and neuronal loss in the brains of tau transgenic mice

Neurofibrillary tangles composed of hyperphosphorylated fibrillized tau are found in numerous tauopathies including Alzheimer's disease. Increasing evidence suggests that tau pathology can be transmitted from cell-to-cell; however the mechanisms involved in the initiation of tau fibrillization...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Neurobiol Dis
Main Authors: Peeraer, Eve, Bottelbergs, Astrid, Van Kolen, Kristof, Stancu, Ilie-Cosmin, Vasconcelos, Bruno, Mahieu, Michel, Duytschaever, Hilde, Ver Donck, Luc, Torremans, An, Sluydts, Ellen, Van Acker, Nathalie, Kemp, John A., Mercken, Marc, Brunden, Kurt R., Trojanowski, John Q., Dewachter, Ilse, Lee, Virginia M.Y., Moechars, Diederik
פורמט: Artigo
שפה:Inglês
יצא לאור: 2014
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303592/
https://ncbi.nlm.nih.gov/pubmed/25220759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2014.08.032
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