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Penetration of Cefamandole, Cephalothin, and Desacetylcephalothin into Fibrin Clots

The conversion of cephalothin into a less active metabolite (desacetylcephalothin) might influence its distribution in tissues. An experimental rabbit model devised to determine concentrations of antibiotics in subcutaneous fibrin clots was used in this study. Groups of five to six animals received...

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Detalles Bibliográficos
Publicado en:Antimicrob Agents Chemother
Principais autores: Bergeron, Michel G., Nguyen, Bach M., Trottier, Sylvie, Gauvreau, Léo
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1977
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC430004/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/931366/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.12.6.682
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