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Penetration of Cefamandole, Cephalothin, and Desacetylcephalothin into Fibrin Clots

The conversion of cephalothin into a less active metabolite (desacetylcephalothin) might influence its distribution in tissues. An experimental rabbit model devised to determine concentrations of antibiotics in subcutaneous fibrin clots was used in this study. Groups of five to six animals received...

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Detalhes bibliográficos
Main Authors: Bergeron, Michel G., Nguyen, Bach M., Trottier, Sylvie, Gauvreau, Léo
Formato: Artigo
Idioma:Inglês
Publicado em: 1977
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC430004/
https://ncbi.nlm.nih.gov/pubmed/931366
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