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Comparative Pharmacokinetics of Cefamandole, Cephapirin, and Cephalothin in Healthy Subjects and Effect of Repeated Dosing

Cefamandole nafate, cephapirin, and cephalothin were administered intravenously in crossover fashion to 12 volunteers, in dosages of 2 g every 6 h for 16 doses. Mean peak levels of cefamandole were approximately 50% higher than those of the other agents. The serum concentration curves appeared to de...

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書目詳細資料
發表在:Antimicrob Agents Chemother
Main Authors: Barza, Michael, Melethil, Srikumaran, Berger, Stephen, Ernst, E. Chaim
格式: Artigo
語言:Inglês
出版: American Society for Microbiology (ASM) 1976
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在線閱讀:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC429764/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/984783/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.10.3.421
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