Comparative Pharmacokinetics of Cefamandole, Cephapirin, and Cephalothin in Healthy Subjects and Effect of Repeated Dosing

Cefamandole nafate, cephapirin, and cephalothin were administered intravenously in crossover fashion to 12 volunteers, in dosages of 2 g every 6 h for 16 doses. Mean peak levels of cefamandole were approximately 50% higher than those of the other agents. The serum concentration curves appeared to de...

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Podrobná bibliografie

Vydáno v:	Antimicrob Agents Chemother
Hlavní autoři:	Barza, Michael, Melethil, Srikumaran, Berger, Stephen, Ernst, E. Chaim
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1976
Témata:	Pharmacology and Therapeutics
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC429764/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/984783/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.10.3.421
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