Comparative Pharmacokinetics of Cefamandole, Cephapirin, and Cephalothin in Healthy Subjects and Effect of Repeated Dosing

Cefamandole nafate, cephapirin, and cephalothin were administered intravenously in crossover fashion to 12 volunteers, in dosages of 2 g every 6 h for 16 doses. Mean peak levels of cefamandole were approximately 50% higher than those of the other agents. The serum concentration curves appeared to de...

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הוצא לאור ב:	Antimicrob Agents Chemother
Principais autores:	Barza, Michael, Melethil, Srikumaran, Berger, Stephen, Ernst, E. Chaim
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	American Society for Microbiology (ASM) 1976
נושאים:	Pharmacology and Therapeutics
גישה מקוונת:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC429764/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/984783/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.10.3.421
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