Comparative Pharmacokinetics of Cefamandole, Cephapirin, and Cephalothin in Healthy Subjects and Effect of Repeated Dosing

Cefamandole nafate, cephapirin, and cephalothin were administered intravenously in crossover fashion to 12 volunteers, in dosages of 2 g every 6 h for 16 doses. Mean peak levels of cefamandole were approximately 50% higher than those of the other agents. The serum concentration curves appeared to de...

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izdano v:	Antimicrob Agents Chemother
Principais autores:	Barza, Michael, Melethil, Srikumaran, Berger, Stephen, Ernst, E. Chaim
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 1976
Teme:	Pharmacology and Therapeutics
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC429764/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/984783/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.10.3.421
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