Penetration of Cefamandole, Cephalothin, and Desacetylcephalothin into Fibrin Clots

The conversion of cephalothin into a less active metabolite (desacetylcephalothin) might influence its distribution in tissues. An experimental rabbit model devised to determine concentrations of antibiotics in subcutaneous fibrin clots was used in this study. Groups of five to six animals received...

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Bibliografiske detaljer

Udgivet i:	Antimicrob Agents Chemother
Principais autores:	Bergeron, Michel G., Nguyen, Bach M., Trottier, Sylvie, Gauvreau, Léo
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1977
Fag:	Pharmacology and Therapeutics
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC430004/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/931366/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.12.6.682
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