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Penetration of Cefamandole, Cephalothin, and Desacetylcephalothin into Fibrin Clots

The conversion of cephalothin into a less active metabolite (desacetylcephalothin) might influence its distribution in tissues. An experimental rabbit model devised to determine concentrations of antibiotics in subcutaneous fibrin clots was used in this study. Groups of five to six animals received...

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Bibliografske podrobnosti
izdano v:Antimicrob Agents Chemother
Main Authors: Bergeron, Michel G., Nguyen, Bach M., Trottier, Sylvie, Gauvreau, Léo
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 1977
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC430004/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/931366/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.12.6.682
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