Penetration of Cefamandole, Cephalothin, and Desacetylcephalothin into Fibrin Clots

The conversion of cephalothin into a less active metabolite (desacetylcephalothin) might influence its distribution in tissues. An experimental rabbit model devised to determine concentrations of antibiotics in subcutaneous fibrin clots was used in this study. Groups of five to six animals received...

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Bibliografische Detailangaben

Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Bergeron, Michel G., Nguyen, Bach M., Trottier, Sylvie, Gauvreau, Léo
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1977
Schlagworte:	Pharmacology and Therapeutics
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC430004/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/931366/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.12.6.682
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