Gli1/DNA interaction is a druggable target for Hedgehog-dependent tumors

Hedgehog signaling is essential for tissue development and stemness, and its deregulation has been observed in many tumors. Aberrant activation of Hedgehog signaling is the result of genetic mutations of pathway components or other Smo-dependent or independent mechanisms, all triggering the downstre...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:EMBO J
Autors principals: Infante, Paola, Mori, Mattia, Alfonsi, Romina, Ghirga, Francesca, Aiello, Federica, Toscano, Sara, Ingallina, Cinzia, Siler, Mariangela, Cucchi, Danilo, Po, Agnese, Miele, Evelina, D'Amico, Davide, Canettieri, Gianluca, De Smaele, Enrico, Ferretti, Elisabetta, Screpanti, Isabella, Uccello Barretta, Gloria, Botta, Maurizio, Botta, Bruno, Gulino, Alberto, Di Marcotullio, Lucia
Format: Artigo
Idioma:Inglês
Publicat: BlackWell Publishing Ltd 2015
Matèries:
Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4298015/
https://ncbi.nlm.nih.gov/pubmed/25476449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201489213
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars