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Rapid modeling of cooperating genetic events in cancer through somatic genome editing
Cancer is a multistep process that involves mutations and other alterations in oncogenes and tumor suppressor genes(1). Genome sequencing studies have identified a large collection of genetic alterations that occur in human cancers(2–4). However, the determination of which mutations are causally rel...
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| Vydáno v: | Nature |
|---|---|
| Hlavní autoři: | , , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4292871/ https://ncbi.nlm.nih.gov/pubmed/25337879 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13906 |
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