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Rapid modeling of cooperating genetic events in cancer through somatic genome editing
Cancer is a multistep process that involves mutations and other alterations in oncogenes and tumor suppressor genes(1). Genome sequencing studies have identified a large collection of genetic alterations that occur in human cancers(2–4). However, the determination of which mutations are causally rel...
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| Publicado no: | Nature |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4292871/ https://ncbi.nlm.nih.gov/pubmed/25337879 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13906 |
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