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The Role of Double-Strand Break Repair Pathways at Functional and Dysfunctional Telomeres

Telomeres have evolved to protect the ends of linear chromosomes from the myriad of threats posed by the cellular DNA damage signaling and repair pathways. Mammalian telomeres have to block nonhomologous end joining (NHEJ), thus preventing chromosome fusions; they need to control homologous recombin...

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Bibliografski detalji
Izdano u:Cold Spring Harb Perspect Biol
Glavni autori: Doksani, Ylli, de Lange, Titia
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4292156/
https://ncbi.nlm.nih.gov/pubmed/25228584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a016576
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