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The Role of Double-Strand Break Repair Pathways at Functional and Dysfunctional Telomeres

Telomeres have evolved to protect the ends of linear chromosomes from the myriad of threats posed by the cellular DNA damage signaling and repair pathways. Mammalian telomeres have to block nonhomologous end joining (NHEJ), thus preventing chromosome fusions; they need to control homologous recombin...

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Xehetasun bibliografikoak
Argitaratua izan da:Cold Spring Harb Perspect Biol
Egile Nagusiak: Doksani, Ylli, de Lange, Titia
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4292156/
https://ncbi.nlm.nih.gov/pubmed/25228584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a016576
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