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The Role of Double-Strand Break Repair Pathways at Functional and Dysfunctional Telomeres
Telomeres have evolved to protect the ends of linear chromosomes from the myriad of threats posed by the cellular DNA damage signaling and repair pathways. Mammalian telomeres have to block nonhomologous end joining (NHEJ), thus preventing chromosome fusions; they need to control homologous recombin...
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| Publicat a: | Cold Spring Harb Perspect Biol |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cold Spring Harbor Laboratory Press
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4292156/ https://ncbi.nlm.nih.gov/pubmed/25228584 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a016576 |
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