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The Role of Double-Strand Break Repair Pathways at Functional and Dysfunctional Telomeres

Telomeres have evolved to protect the ends of linear chromosomes from the myriad of threats posed by the cellular DNA damage signaling and repair pathways. Mammalian telomeres have to block nonhomologous end joining (NHEJ), thus preventing chromosome fusions; they need to control homologous recombin...

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Bibliografische gegevens
Gepubliceerd in:Cold Spring Harb Perspect Biol
Hoofdauteurs: Doksani, Ylli, de Lange, Titia
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cold Spring Harbor Laboratory Press 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4292156/
https://ncbi.nlm.nih.gov/pubmed/25228584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a016576
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