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The MRN complex in Double-Strand Break Repair and Telomere Maintenance
Genomes are subject to constant threat by damaging agents that generate DNA double-strand breaks (DSBs). The ends of linear chromosomes need to be protected from DNA damage recognition and end-joining, and this is achieved through protein-DNA complexes known as telomeres. The Mre11-Rad50-Nbs1 (MRN)...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2946096/ https://ncbi.nlm.nih.gov/pubmed/20655309 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2010.07.029 |
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