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Functional and structural insights into the MRX/MRN complex, a key player in recognition and repair of DNA double-strand breaks
Chromosomal DNA double-strand breaks (DSBs) are potentially lethal DNA lesions that pose a significant threat to genome stability and therefore need to be repaired to preserve genome integrity. Eukaryotic cells possess two main mechanisms for repairing DSBs: non-homologous end-joining (NHEJ) and hom...
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| Vydáno v: | Comput Struct Biotechnol J |
|---|---|
| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Research Network of Computational and Structural Biotechnology
2020
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7260605/ https://ncbi.nlm.nih.gov/pubmed/32489527 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2020.05.013 |
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