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Mdt1 Facilitates Efficient Repair of Blocked DNA Double-Strand Breaks and Recombinational Maintenance of Telomeres

DNA recombination plays critical roles in DNA repair and alternative telomere maintenance. Here we show that absence of the SQ/TQ cluster domain-containing protein Mdt1 (Ybl051c) renders Saccharomyces cerevisiae particularly hypersensitive to bleomycin, a drug that causes 3′-phospho-glycolate-blocke...

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Detalles Bibliográficos
Main Authors: Pike, Brietta L., Heierhorst, Jörg
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2099617/
https://ncbi.nlm.nih.gov/pubmed/17636027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00471-07
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