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Telomere Dysfunction Triggers Palindrome Formation Independently of Double-Strand Break Repair Mechanisms

Inverted chromosome duplications or palindromes are linked with genetic disorders and malignant transformation. They are considered by-products of DNA double-strand break (DSB) repair: the homologous recombination (HR) and the nonhomologous end joining (NHEJ). Palindromes near chromosome ends are of...

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Bibliografiske detaljer
Udgivet i:Genetics
Main Authors: Raykov, Vasil, Marvin, Marcus E., Louis, Edward J., Maringele, Laura
Format: Artigo
Sprog:Inglês
Udgivet: Genetics Society of America 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4981268/
https://ncbi.nlm.nih.gov/pubmed/27334270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.115.183020
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