Unfolded protein response-induced ERdj3 secretion links ER stress to extracellular proteostasis

The Unfolded Protein Response (UPR) indirectly regulates extracellular proteostasis through transcriptional remodeling of endoplasmic reticulum (ER) proteostasis pathways. This remodeling attenuates secretion of misfolded, aggregation-prone proteins during ER stress. Through these activities, the UP...

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Vydáno v:EMBO J
Hlavní autoři: Genereux, Joseph C, Qu, Song, Zhou, Minghai, Ryno, Lisa M, Wang, Shiyu, Shoulders, Matthew D, Kaufman, Randal J, Lasmézas, Corinne I, Kelly, Jeffery W, Wiseman, R Luke
Médium: Artigo
Jazyk:Inglês
Vydáno: BlackWell Publishing Ltd 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291477/
https://ncbi.nlm.nih.gov/pubmed/25361606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201488896
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