Unfolded protein response-induced ERdj3 secretion links ER stress to extracellular proteostasis

The Unfolded Protein Response (UPR) indirectly regulates extracellular proteostasis through transcriptional remodeling of endoplasmic reticulum (ER) proteostasis pathways. This remodeling attenuates secretion of misfolded, aggregation-prone proteins during ER stress. Through these activities, the UP...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Genereux, Joseph C, Qu, Song, Zhou, Minghai, Ryno, Lisa M, Wang, Shiyu, Shoulders, Matthew D, Kaufman, Randal J, Lasmézas, Corinne I, Kelly, Jeffery W, Wiseman, R Luke
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291477/
https://ncbi.nlm.nih.gov/pubmed/25361606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201488896
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