Targeting unfolded protein response signaling pathways to ameliorate protein misfolding diseases

Por Ryno, Lisa M, Wiseman, R Luke, Kelly, Jeffery W
Publicado no Curr Opin Chem Biol (2013)

Broadly Applicable Methodology for the Rapid and Dosable Small Molecule-Mediated Regulation of Transcription Factors in Human Cells

Por Shoulders, Matthew D., Ryno, Lisa M., Cooley, Christina B., Kelly, Jeffery W., Wiseman, R. Luke
Publicado em 2013

Characterizing the Altered Cellular Proteome Induced by the Stress-Independent Activation of Heat Shock Factor 1

Por Ryno, Lisa M., Genereux, Joseph C., Naito, Tadasuke, Morimoto, Richard I., Powers, Evan T., Shoulders, Matthew D., Wiseman, R. Luke
Publicado em 2014

Unfolded protein response activation reduces secretion and extracellular aggregation of amyloidogenic immunoglobulin light chain

Por Cooley, Christina B., Ryno, Lisa M., Plate, Lars, Morgan, Gareth J., Hulleman, John D., Kelly, Jeffery W., Wiseman, R. Luke
Publicado no Proc Natl Acad Sci U S A (2014)

Molecular Recognition of Insulin by a Synthetic Receptor

Por Chinai, Jordan M., Taylor, Alexander B., Ryno, Lisa M., Hargreaves, Nicholas D., Morris, Christopher A., Hart, P. John, Urbach, Adam R.
Publicado em 2011

Unfolded protein response-induced ERdj3 secretion links ER stress to extracellular proteostasis

Por Genereux, Joseph C, Qu, Song, Zhou, Minghai, Ryno, Lisa M, Wang, Shiyu, Shoulders, Matthew D, Kaufman, Randal J, Lasmézas, Corinne I, Kelly, Jeffery W, Wiseman, R Luke
Publicado no EMBO J (2015)

Stress-Independent Activation of XBP1s and/or ATF6 Reveals Three Functionally Diverse ER Proteostasis Environments

Por Shoulders, Matthew D., Ryno, Lisa M., Genereux, Joseph C., Moresco, James J., Tu, Patricia G., Wu, Chunlei, Yates, John R., Su, Andrew I., Kelly, Jeffery W., Wiseman, R. Luke
Publicado em 2013