Molecular Basis of Histone Tail Recognition by Human TIP5 PHD Finger and Bromodomain of the Chromatin Remodeling Complex NoRC

Binding of the chromatin remodeling complex NoRC to RNA complementary to the rDNA promoter mediates transcriptional repression. TIP5, the largest subunit of NoRC, is involved in recruitment to rDNA by interactions with promoter-bound TTF-I, pRNA, and acetylation of H4K16. TIP5 domains that recognize...

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Publicado no:Structure
Main Authors: Tallant, Cynthia, Valentini, Erica, Fedorov, Oleg, Overvoorde, Lois, Ferguson, Fleur M., Filippakopoulos, Panagis, Svergun, Dmitri I., Knapp, Stefan, Ciulli, Alessio
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291147/
https://ncbi.nlm.nih.gov/pubmed/25533489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2014.10.017
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