Modeling Fanconi Anemia pathogenesis and therapeutics using integration-free patient-derived iPSCs

Fanconi Anemia (FA) is a recessive disorder characterized by genomic instability, congenital abnormalities, cancer predisposition and bone marrow failure. However, the pathogenesis of FA is not fully understood partly due to the limitations of current disease models. Here, we derive integration-free...

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Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: Liu, Guang-Hui, Suzuki, Keiichiro, Li, Mo, Qu, Jing, Montserrat, Nuria, Tarantino, Carolina, Gu, Ying, Yi, Fei, Xu, Xiuling, Zhang, Weiqi, Ruiz, Sergio, Plongthongkum, Nongluk, Zhang, Kun, Masuda, Shigeo, Nivet, Emmanuel, Tsunekawa, Yuji, Soligalla, Rupa Devi, Goebl, April, Aizawa, Emi, Kim, Na Young, Kim, Jessica, Dubova, Ilir, Li, Ying, Ren, Ruotong, Benner, Chris, del Sol, Antonio, Bueren, Juan, Trujillo, Juan Pablo, Surralles, Jordi, Cappelli, Enrico, Dufour, Carlo, Esteban, Concepcion Rodriguez, Belmonte, Juan Carlos Izpisua
Format: Artigo
Langue:Inglês
Publié: 2014
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291073/
https://ncbi.nlm.nih.gov/pubmed/24999918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5330
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