Modeling xeroderma pigmentosum associated neurological pathologies with patients-derived iPSCs

Xeroderma pigmentosum (XP) is a group of genetic disorders caused by mutations of XP-associated genes, resulting in impairment of DNA repair. XP patients frequently exhibit neurological degeneration, but the underlying mechanism is unknown, in part due to lack of proper disease models. Here, we gene...

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Vydáno v:Protein Cell
Hlavní autoři: Fu, Lina, Xu, Xiuling, Ren, Ruotong, Wu, Jun, Zhang, Weiqi, Yang, Jiping, Ren, Xiaoqing, Wang, Si, Zhao, Yang, Sun, Liang, Yu, Yang, Wang, Zhaoxia, Yang, Ze, Yuan, Yun, Qiao, Jie, Belmonte, Juan Carlos Izpisua, Qu, Jing, Liu, Guang-Hui
Médium: Artigo
Jazyk:Inglês
Vydáno: Higher Education Press 2016
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4791426/
https://ncbi.nlm.nih.gov/pubmed/26874523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-016-0244-y
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