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Modeling xeroderma pigmentosum associated neurological pathologies with patients-derived iPSCs

Xeroderma pigmentosum (XP) is a group of genetic disorders caused by mutations of XP-associated genes, resulting in impairment of DNA repair. XP patients frequently exhibit neurological degeneration, but the underlying mechanism is unknown, in part due to lack of proper disease models. Here, we gene...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Protein Cell
Main Authors: Fu, Lina, Xu, Xiuling, Ren, Ruotong, Wu, Jun, Zhang, Weiqi, Yang, Jiping, Ren, Xiaoqing, Wang, Si, Zhao, Yang, Sun, Liang, Yu, Yang, Wang, Zhaoxia, Yang, Ze, Yuan, Yun, Qiao, Jie, Belmonte, Juan Carlos Izpisua, Qu, Jing, Liu, Guang-Hui
פורמט: Artigo
שפה:Inglês
יצא לאור: Higher Education Press 2016
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4791426/
https://ncbi.nlm.nih.gov/pubmed/26874523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-016-0244-y
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