Modeling xeroderma pigmentosum associated neurological pathologies with patients-derived iPSCs

Xeroderma pigmentosum (XP) is a group of genetic disorders caused by mutations of XP-associated genes, resulting in impairment of DNA repair. XP patients frequently exhibit neurological degeneration, but the underlying mechanism is unknown, in part due to lack of proper disease models. Here, we gene...

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Pubblicato in:Protein Cell
Autori principali: Fu, Lina, Xu, Xiuling, Ren, Ruotong, Wu, Jun, Zhang, Weiqi, Yang, Jiping, Ren, Xiaoqing, Wang, Si, Zhao, Yang, Sun, Liang, Yu, Yang, Wang, Zhaoxia, Yang, Ze, Yuan, Yun, Qiao, Jie, Belmonte, Juan Carlos Izpisua, Qu, Jing, Liu, Guang-Hui
Natura: Artigo
Lingua:Inglês
Pubblicazione: Higher Education Press 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4791426/
https://ncbi.nlm.nih.gov/pubmed/26874523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-016-0244-y
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